简历:
2007.9 – 2013.6 江南大学 食品科学 工学博士
2008.9 – 2013.3 南开大学 泰达生物技术公司 联合培养博士
2003.9 – 2007.6 江南大学 食品科学与工程 工学学士
研究方向:
基于肠道微生态大数据的精准膳食干预
肠道菌群与人体互作关系的深度挖掘
国家自然科学基金面上项目,基于肠道菌群多维数据模型挖掘调节能量代谢的益生菌(32172212);
国家自然科学基金青年项目,高山被孢霉脂质合成与苯丙氨酸代谢相关性及调控机制研究(31400038);
代谢疾病人群肠道菌群特征及特殊膳食开发,无锡市人民医院
1.Hongchao Wang,Haiqin Chen, Guangfei Hao, Bo Yang, Yun Feng, Yu Wang, Lu Feng, Jianxin Zhao,Yuanda Song, Hao Zhang, Y. Q. Chen, Lei Wang, and Wei Chen. 2013. Role of thePhenylalanine hydroxylating system in lipid metabolism and aromatic substancedegradation in the oleaginous fungus Mortierellaalpina, Applied and Environmental Microbiology, doi:10.1128/AEM.00238-13.
2.Hongchao Wang,Bo Yang, Guangfei Hao, Yun Feng, Haiqin Chen, Lu Feng, Jiangxin Zhao, HaoZhang, Y. Q. Chen, Lei Wang, and Wei Chen. 2011. Biochemical characterizationof the tetrahydrobiopterin synthesis pathway in the oleaginous fungusMortierella alpina, Microbiology-SGM157:3059-70.
3. Wang Lei, Wei Chen, Yun Feng, Yan Ren, Zhennan Gu,Haiqin Chen,Hongchao Wang, et all.2011. Genome characterization of the oleaginous fungus Mortierella alpina. PLoS One 6:e28319.
4. ChenH, Hao G, Wang L,Wang H,Gu Z, Liu L, Zhang H, Chen W*, Chen Y Q*. Identification of a criticaldeterminant that enables efficient fatty acid synthesis in oleaginous fungi. Scientific Reports, 2015, 5: 11247.
5.Hongchao Wang, Haiqin Chen, Hao Zhang, Wei Chen, and Y. Q. Chen. Characterization of a Fungal L-fucokinase involved inMortierella alpinaGDP-L-fucose Salvage Pathway, Glycobiology, 2016.8.
6. Wu, Tong; Wang, Hongchao*; Lu, Wenwei; Zhai, Qixiao; Zhang, Qiuxiang; Yuan, Weiwei; Gu, Zhennan; Zhao, Jianxin; Zhang, Hao; Chen, Wei; Potential of gut microbiome for detection of autism spectrum disorder , Microbial Pathogenesis, 2020, 149(12): 1-10.
7.Wang, Hongchao#; Zhang, Chen#; Chen, Haiqin; Gu, Zhennan; Zhao, Jianxin; Zhang, Hao; Chen, Yong Q.; Chen, Wei*; Tetrahydrobiopterin plays a functionallysignificant role in lipogenesis in the oleaginous fungus Mortierella alpina, Frontiers in Microbiology, 2020, 11(2): 1-11.
8.Weiwei Yuan, Wenwei Lu, Hongchao Wang, Wenjun Wu, Qunyan Zhou, Yutao Chen, Yuan Kun Lee, Jianxin Zhao, Hao Zhang & Wei Chen (2021): A multiphase dietetic protocol incorporating an improved ketogenic diet enhances weight loss and alters the gut microbiome of obese people, International Journal of Food Sciences and Nutrition, DOI:10.1080/09637486.2021.1960957
9.Chen, Y.; Wu, T.; Lu, W.;Yuan, W.; Pan, M.; Lee, Y.-K.; Zhao, J.;Zhang, H.; Chen, W.; Zhu, J.; et al.Predicting the Role of the Human Gut Microbiome in Constipation Using Machine-Learning Methods: A Meta-Analysis. Microorganisms 2021, 9, 2149.https://doi.org/10.3390/microorganisms9102149
10.Yutao Chen,Hongchao Wang,Wenwei Lu,Tong Wu,Weiwei Yuan,Jinlin Zhu,Yuan Kun Lee,Jianxin Zhao,Hao Zhang,Wei Chen. Human gut microbiome aging clocks based on taxonomic and functional signatures through multi-view learning. Gut Microbes. 2022. doi: 10.1080/19490976.2021.2025016
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